Vitiligo and Rise in Blood Pressure - a Case-Control Study in a Referral Dermatology Clinic in Southern Iran.

PURPOSE: Vitiligo is an acquired hypopigmentation condition in which well-defined macules can develop virtually everywhere on the patients' skin. This analytic case-control study was conducted in Faghihi Hospital outpatient dermatology clinic, affiliated to Shiraz University of Medical Sciences, southern Iran from June to September 2019. Furthermore, we studied the relationship of hypertension with activity, age of onset, duration, affected body surface area and type of vitiligo. PATIENTS AND METHODS: In the current case-control study, 166 individuals were enrolled in total (the case group was comprised of 83 vitiligo patients and 83 individuals actedas control group). The case group was made up of vitiligo patients (both segmental and non-segmental) between 20 and 50 years of age, no prior history of systemic disease and other hypopigmentation disorders, while individuals with any form of dermatologic findings were excluded from the control group. Individuals aged younger than 20 years old or older than 50, having a dermatologic disease other than vitiligo, being afflicted with the diseases which may lead to secondary hypertension, pregnancy, taking substances, and medication which can lead to hypertension were chosen as the exclusion criteria in this study. RESULTS: Data obtained from our study revealed that vitiligo patients had a higher prevalence of essential hypertension diagnosis than the control group (P=0.040). Also, no significant relationship was found between patients' age at the first lesion appearance (P=0.856), duration of vitiligo involvement (P=0.497), and percentage of vitiligo involvement (P=0.681) with hypertension. CONCLUSION: According to our results, vitiligo patients were more susceptible to hypertension while no association could be found between characteristics of the disease and rise in blood pressure.

Stenotrophomonas maltophilia right-sided endocarditis in an adult patient with uncorrected congenital heart disease.

•Stenotrophomonas maltophilia is a Gram negative, low virulence, one of the leading multiple-drug-resistant pathogen and quite often causes nosocomial infection.•Bacteremia with Stenotrophomonas maltophilia has higher mortality than Pseudomonas aeruginosa.•Stenotrophomonas maltophilia endocarditis is too scarce, however, it accompanied with high rates of mortality and morbidity.•Acute bacterial endocarditis due to Stenotrophomonas maltophilia can occur even in patients with uncorrected congenital heart disease and lack of immune deficiency, therefore. clinicians should be aware.

Device closure in adults with atrial septal defect in Shiraz, a single center registry.

INTRODUCTION: Successful closure of atrial septal defect (ASD) improves patients' functional class and exercise capacity. In this study we evaluate the safety and feasibility of percutaneous device closure of ASDs. METHODS: Two hundred fifty six patients with significant ASD according to our criteria were enrolled. The patients were treated using nitinol wire mesh transcatheter devices. Complications were followed for a median of 2.5 years. RESULTS: Success rate was 98.4% with 3 unsuccessful cases and a mean hospital stay of 1.007 ± 0.0004 days. Complication rate was 7.42%. Size of the right ventricle (RV) annulus was significantly decreased 24 hours after intervention (P = 0.005). CONCLUSION: The present report demonstrates that transcatheter closure of ASD is safe and effective.